Inpatient treatment of pneumonia, according to 2009 Joint Commission and the Centers for Medicare and Medicaid Services consensus guidelines, should be given within 6 hours of hospital admission (or in the emergency department if this is where the patient initially presented) and should consist of the following antibiotic regimens32 :
Non-ICU patients (choice of one option)
Beta-lactam (IV or IM) plus macrolide (IV or PO)
Antipneumococcal quinolone monotherapy (IV or IM)
Beta-lactam (IV or IM) plus doxycycline (IV or oral)
If patient younger than 65 years with no risk factors for drug-resistant pneumococcus - Macrolide monotherapy (IV or oral)
ICU Patients (choice of one option)
Beta-lactam (IV) plus macrolide (IV)
Beta-lactam (IV) plus antipneumococcal quinolone (IV)
If patient has documented beta-lactam allergy - Antipneumococcal quinolone (IV) plus aztreonam (IV)
Patients at increased risk of infection with Pseudomonas (acceptable for both ICU and non-ICU patients) (choice of one option)
Antipseudomonal beta-lactam (IV) plus antipseudomonal quinolone (IV; PO in non-ICU only)
Antipseudomonal beta-lactam (IV) plus aminoglycoside (IV) plus one of the following:
Macrolide (IV)
Antipneumococcal quinolone (IV; PO in non-ICU only)
If patient has documented beta-lactam allergy - Aztreonam (IV) plus aminoglycoside (IV) plus antipneumococcal quinolone (IV; PO in non-ICU only)
For very nice Details about AB:
http://emedicine.medscape.com/articl...tnew_nl_0#meds
best wishes,,
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